Original Research Article
Year: 2018 | Month: April | Volume: 8 | Issue: 4 | Pages: 38-44
Implications of Glucose and Creatinine Concentration in Relation to Obesity among the Students of Faculty of Health Science and Technology in Ebonyi State University, Abakaliki, Nigeria
Okoro, Godwin O1, Onyenekwe Charles C1, Fasogbon, Samuel Ayobami2, Okorie Nnaemeka3
1Department of Medical Laboratory Sciences, Ebonyi State University, Abakaliki, Ebonyi State, Nigeria
2Public Health In-vitro Diagnostic Control Laboratory, Medical Laboratory Science Council of Nigeria,
Lagos State, Nigeria
3N.K.S.T. Len Gebrielse’ School of Medical Laboratory Science Mkar, Benue State, Nigeria
Corresponding Author: Fasogbon, Samuel Ayobami
ABSTRACT
Background: The prevalence of obesity is on the rise and it’s now widely recognized as a risk factor for cardiovascular diseases, chronic kidney diseases and other metabolic disorders such as diabetes mellitus type 2. The aim of this study is to know the relationship between body mass index (BMI) in respect to glucose and creatinine clearance in the body.
Materials and Methods: The mean age for the males was 25±7 years while the mean age for the females were 24±5years. The proportion of study population that was overweight and obese was 21.1% and 26.3% respectively.
Result and Discussion: The mean plasma creatinine (male, 120.29±22.14; female, 87.96±16.92; p=0.000) and WHR (male, 0.84±0.039; female, 0.81±0.6; p= 0.003) were all significantly higher in males when compared with that of the females. In the present study, the plasma creatinine level of obese subjects appeared to be insignificantly correlated with BMI and MUAC. BMI showed an insignificant but a negative correlation with plasma creatinine levels in female obese subjects whereas it showed a positive correlation in male obese subjects. However there was no correlation between fasting glucose level of obese female students and their BMI (r= -0.03, p= 0.921) but fasting glucose level was observed to be positively and insignificantly correlated with MUAC (r= 0.236, p= 0.437). The relationship was negatively and weakly correlated among the male subjects (BMI; r= -0.244, p= 0.756 and MUAC; r=-0.213 and p= 0.787).
Conclusion: This study shows that obesity is more correlated with plasma creatinine level than fasting glucose level and can be a predictor of kidney damage. When considering the entire subjects, the mean values of fasting glucose in gender were similar and insignificant.
Key words: Glucose, Creatinine, Obesity, BMI.