Original Research Article
Year: 2017 | Month: September | Volume: 7 | Issue: 9 | Pages: 90-95
Investigation of Antibacterial Activity of Different Extracts of Barleria Cristata Leaves
B. Sumaya Sulthana1, E. Honey1, B. Anasuya1, H. Gangarayudu2, M. Jyothi Reddy2, C. Girish1
1S.V.U.College of Pharmaceutical Sciences, Sri Venkateshwara University, Tirupati - 517502. A.P, India.
2Sri Lakshmi Venkateswara Institute of Pharmaceutical Sciences, Proddutur, Kadapa dt, A.P, India.
Corresponding Author: C. Girish
ABSTRACT
The antibacterial activity of the methanol and aqueous extracts of the leaves of Barleria cristata was investigated against Gram positive organism Streptococcus pyogenes and Gram negative organism Escherichia coli NCTC 10418 using well diffusion technique. Results showed that the methanolic extracts of Barleria cristata were effective against the test microorganisms. The percentage of zone of inhibition on E. coli by methanolic extract and aqueous extract is 77.06 and 64.2 respectively and the percentage of zone of inhibition on Streptococcus by methanolic extract and aqueous extract is 78.5 and 68.8 respectively. The results of the study provide scientific basis for the use of the plant extract in the treatment of wounds and skin diseases.
Key words: Barleria cristata, Streptococcus pyogenes, Escherichia coli, Well diffusion technique and Antibacterial activity.