Original Research Article
Year: 2017 | Month: July | Volume: 7 | Issue: 7 | Pages: 280-289
The Effect of Adjuvant Chemotherapy on Anthropometric Measurements, Energy and Nutrient İntake in Breast Cancer Patients
Ozlem Muhsiroglu1, Cengizhan Acikel2, Fikret Arpaci3, Neslisah Rakicioglu4
1Gulhane Research and Education Hospital Department of Medical Oncology. Etlik Ankara/TURKEY.
2Gulhane Research and Education Hospital Department of Bioistatistic. Etlik Ankara/TURKEY-
3Liv Hospital Department of Medical Oncology. Ankara/TURKEY.
4Hacettepe University Faculty of Health Science Department of Nutrition and Dietetics- Ankara/TURKEY.
Corresponding Author: Neslisah Rakicioglu
ABSTRACT
The aim of this study was to examine the effect of adjuvant chemotherapy on intakes of energy, nutrient, anthropometric measurements in patients with breast cancer. The study included 20-64 years old, 21 patients with newly diagnosed non-metastatic breast cancer that were scheduled for adjuvant chemotherapy. The patients were followed-up during 4-6 courses of chemotherapy. 3-day food consumption, 24-hour physical activity record, anthropometric measurements, some blood biochemistry, body composition analysis and resting metabolic rate (RMR) measurements using the bioelectrical impedance were recorded on 3 period: before, during, after chemotherapy. It was found that patients’s energy and fat intakes did not change during chemotherapy according to before chemotherapy, but after chemotherapy, energy and fat intakes reduced than during chemotherapy. Patients’ energy balance was evaluated. According to before chemotherapy, patients’ energy intakes did not change but energy expenditure decreased significantly during chemotherapy. After chemotherapy, both energy intake and expenditure decreased significantly. RMR measurementswere not different. Weight and body mass index (BMI) did not change but waist, hip, mid-upper-arm circumferences measurements and body fat mass increased during and after chemotherapy than before chemotherapy. So this result indicate that during treatment, despite a decrease in energy expenditure due to a decrease in physical activity, an increase in energy intake and/or a failure to decrease energy intake that might have caused the observed increase in body fat-mass.
Key words: Breast cancer, adjuvant chemotherapy, food intake, anthropometric measurement, body composition.