Case Report
Year: 2017 | Month: May | Volume: 7 | Issue: 5 | Pages: 388-392
Paradoxical Reaction in an Immunocompetent Internal Medicine Resident Suffering from Tubercular Lymphadenitis
N.S Neki1, Neeraj Joshi2, Gagandeep Singh Shergill2, Amritpal Singh3, Narendra Kumar Meena2,Amanpreet Kaur4, Amandeep Singh Dhanju2, Aarti Vaid2, Deepali Kausahal2
1Professor, 2Junior Resident, 3Senior Resident,
Department Of Medicine, Govt. Medical College and Guru Nanak Dev Hospital, Amritsar, India, 143001
4Consultant Gynaecologist, District Hospital, Fatehgarh Sahib, Punjab, India.
Corresponding Author: N.S Neki
ABSTRACT
A tuberculosis associated Paradoxical Reaction (PR), aka tuberculosis associated immune reconstitution inflammatory syndrome (TB-IRIS) is defined as the worsening of clinical or radiological findings, following the initiation of appropriate antitubercular treatment, in the absence of evidence of disease relapse or any another probable diagnosis. PR is not uncommon. It is reported in up to 35% of immunocompromised patients with HIV co-infection and in fewer than 5% of immunocompetent patients. We are presenting a case of PR in an immunocompetent host, who is an internal medicine resident, discussing the entity and also highlighting the occupational health hazards in health care workers (HCWs).
Key words: Paradoxical reactions (PR) in tuberculosis; PR in an immuncompetent host; TB-IRIS; Nosocomial TB in HCWs.