Original Research Article
Year: 2017 | Month: February | Volume: 7 | Issue: 2 | Pages: 127-131
Study of Antibiotic Susceptibility Profile of Pseudomonas Aeruginosa in a Tertiary Care Hospital
Dr. Sanchari Das1, Dr. Silpi Basak2
1Post Graduate Student, 2Professor,
Department of Microbiology, Jawaharlal Nehru Medical College, Wardha (MS), Pin-442004
Corresponding Author: Dr. Silpi Basak
ABSTRACT
Background: Pseudomonas aeruginosa is one of the most important cause of Health care associated infections and it develops resistance to most of the commonly used antimicrobials and even to reserve drugs like Carbapenems and Colistin. The antimicrobial resistance mainly develops due to misuse and overuse of antimicrobials.
Aim: Hence the present study was undertaken to study antibiotic susceptibility profile of Pseudomonas aeruginosa, isolated from different clinical samples. Material & methods: Pseudomonas aeruginosa strains were isolated from different clinical samples and were characterized by conventional methods. Antibiotic susceptibility test of Pseudomonas aeruginosa strains were done by Kirby Bauer disc diffusion method as per CLSI Guidelines.
Results: The highest 99.3% Pseudomonas aeruginosa strains were sensitive to Colistin, followed by Aztreonam (97%). The lowest sensitivity was observed with Ceftazidime (16%) and Piperacillin (40%) respectively. Maximum 40% Pseudomonas aeruginosa strains were isolated from pus and wound swab.
Conclusion: Antibiotic susceptibility test for Pseudomonas aeruginosa strains should be routinely done to get a good therapeutic outcome for the patient.
Key words: Pseudomonas aeruginosa, Antibiotic susceptibility test, Kirby Bauer method.