Case Report
Year: 2016 | Month: December | Volume: 6 | Issue: 12 | Pages: 368-371
A Rare Case Report on Chronic Neutrophilic Leukemia with Review of Literature
Priyanka Gupta1, Kishore Shaw2, Raka Hota1, Sukumar Chakravarty3
12nd Year PG Student, Department of Pathology, Hi Tech Medical College & Hospital, Bhubaneswar, Odisha.
2Clinical Tutor, Department of Medicine, College of Medicine & JNM Hospital, Kalyani, West Bengal.
3Professor, Department of Pathology, Hi Tech Medical College & Hospital, Bhubaneswar, Odisha.
Corresponding Author: Priyanka Gupta
ABSTRACT
Chronic neutrophilic leukemia (CNL) is a very rare myeloproliferative neoplasm (MPN) of elderly characterized by sustained neutophilic leucocytosis (>25000/cumm). Considering its rare entity, herein we report a case of CNL in an 80year old man who presented with dyspnoea, pleurisy and PUO. Persistent neutrophilic leukocytosis in a case of PUO in an elderly patient similar to this case can lead to a mistaken underdiagnosis. Suspicion is therefore required, to diagnose a case as CNL, if a patient presents with sustained neutrophilic leukocytosis without any underlying cause, not responding to higher antibiotics.
Key words: CNL, MPN, PUO, Sustained neutrophilic leukocytosis.