Original Research Article
Year: 2016 | Month: December | Volume: 6 | Issue: 12 | Pages: 74-77
A Study of Metallo Beta Lactamase Production in Clinical Isolates of Imipenem Resistant Gram Negative Bacilli
P. Kanchanadevi1, S. Chandra sekaran2
1Lecturer, Dept. of Microbiology, CSI College of Dental Sciences and Research, East Veli, Madurai. India.
2Professor, Department of Microbiology, NIMRA Institute of Medical Sciences, NIMRA Nagar, Jupudi Village, Ibrahimpatnam, Mandal. Krishna dt. Vijayawada, Andhra Pradesh.
Corresponding Author: P. Kanchanadevi
ABSTRACT
In the clinical isolates of Gram negative Bacilli, Metallo Beta lactamases (MBL) production had been seen. Isolates resistant to Imipenem were screened for MBL production by EDS (EDTA Disc Synergy) test, Modified Hodge test and MIC Reduction test. There was comparison among these methods. Rapid detection of MBL producing Gram negative bacilli is necessary to prevent their dissemination and also it provides therapeutic guidance.
Key words: MBL (Metallo Beta Lactamase), MIC (Minimal Inhibitory Concentration), EDS (EDTA Disc Synergy).