Original Research Article
Year: 2014 | Month: January | Volume: 4 | Issue: 1 | Pages: 74-78
Assessment of the Serum Levels of Thyroid Hormones and Thyroid Stimulating Hormone among Sudanese with Type 1 Diabetes Mellitus
Omer I. Abdalla1, Bader Eldien H. Elabid2, Akram H. Awadalla3*
1PGD Clinical Chemistry Division, Elribat National Hospital.
2Associate Professor of Clinical Pathology, University of Science and Technology.
3Assistant Professor of Clinical Chemistry, College of Applied Medical Sciences, Jazan University, KSA.
*Corresponding Author: Iyanam Victory Edet
ABSTRACT
The aim of this study was to assess the serum levels of thyroid hormones (T3, T4) and Thyroid Stimulating Hormone (TSH) among Sudanese with type 1 diabetes mellitus in comparison with apparently healthy individuals as a control group and to determine the relationship between these hormones and the duration of diabetes. A case-control study was conducted during the period from December 2012 up to august 2013in Khartoum state among 500 Sudanese with type 1 diabetes mellitus patients and 250 healthy controls for comparison. The serum levels of Thyroid Hormones (T3, T4) and Thyroid Stimulating Hormones (TSH) were measured using full automated chemistry analyzer (Elecsys 2010) and commercial kits from Roche Diagnostic. The results of this study showed the means of the serum levels of Thyroid Hormones (T3, T4) of diabetics group were significantly raised when compared to the control group, whereas the means of serum level of TSH of the diabetic group were significantly reduced when compared to the control group. The study showed a significant strong positive correlation between the duration of diabetes (in years) and the serum levels of T4 (r=0.98), whereas it showed an insignificant weak positive correlation between the duration of diabetes and the serum levels of TSH (r=0.03).This suggests a relationship between type 1 diabetes and Thyroid disorders.
Key words:Type 1 diabetes mellitus, Thyroid stimulating hormone and Thyroid hormone.