Year: 2026 | Month: September | Volume: 16 | Issue: 9 | Pages: 255-259
DOI: https://doi.org/10.52403/ijhsr.20260926
Squamous Cell Carcinoma Arising in a Mature Pelvic Teratoma in an Adult Male with Situs Inversus Totalis: A Rare Case Scenario
Akansha Jain1, Priyansha Priya2, Arun3, Sachin Kumar4, Bhavana Tiwari5
1,2,3,4,5Department of General Surgery,
Vardhman Mahavir Medical College, Guru Gobind Singh Indraprastha University,
New Delhi, India.
Corresponding Author: Dr. Akansha Jain
ABSTRACT
Background: Extragonadal pelvic teratomas are extremely rare in adult males and may pose significant diagnostic and therapeutic challenges. Malignant transformation within a mature cystic teratoma is uncommon, with squamous cell carcinoma being the most frequent histological subtype. Association with situs inversus totalis is exceedingly rare.
Case Presentation: A 43-year-old man presented with a progressively enlarging abdominal lump for 7 years, with rapid increase in size over the preceding 2 months accompanied by abdominal pain, constipation, altered micturition, and significant weight loss. Clinical examination revealed a large firm abdominopelvic mass occupying all abdominal quadrants. Imaging demonstrated mature teratoma with malignant transformation. Incidentally, situs inversus totalis was identified. Tumor markers including AFP and β-hCG were within normal limits. The patient underwent exploratory laparotomy with adhesiolysis, excision of the cystic mass, and peritoneal lavage. Histopathology revealed mature cystic teratoma with squamous cell carcinoma transformation and metastatic deposits in the cyst base. Postoperative recovery was uneventful, and the patient was planned for adjuvant chemoradiotherapy.
Conclusion: Adult male pelvic teratomas are exceptionally rare and should be considered in the differential diagnosis of large pelvic masses. Rapid enlargement, large tumor size, and solid enhancing nodules may indicate malignant transformation. Complete surgical excision remains the cornerstone of management.
Key words: Pelvic teratoma; Mature cystic teratoma; Squamous cell carcinoma; Extragonadal germ cell tumor; Situs inversus totalis