Year: 2024 | Month: May | Volume: 14 | Issue: 5 | Pages: 210-214
DOI: https://doi.org/10.52403/ijhsr.20240525
Disseminated Fixed Drug Eruption: Unmasking a Rare Presentation of Furazolidone and Metronidazole Combination Therapy
Saurabh1, Praveen Kumar Rathore2, Pushpendra Singh3, Ashwin Charaniya4, Akanksha Singh5
1Junior Resident III year Department of Skin Rohilkhand Medical College, Bareilly Uttar Pradesh, India
2Professor & Head Department of Skin Rohilkhand Medical College, Bareilly Uttar Pradesh, India
3Junior Resident III year Department of Skin Rohilkhand Medical College, Bareilly Uttar Pradesh, India
4Assistant Professor Department of Skin Rohilkhand Medical College, Bareilly Uttar Pradesh, India
5Associate Professor, PhD Scholar Department of Periodontology Institute of Dental Sciences, Bareilly Uttar Pradesh, India
Corresponding Author: Akanksha Singh
ABSTRACT
Fixed drug eruption (FDE) is an uncommon cutaneous adverse reaction characterized by recurrent erythematous or violaceous plaques at fixed sites upon re-exposure to the culprit drug. We present a case of disseminated FDE in a 45-year-old male who developed widespread erythematous lesions involving multiple body sites following concurrent administration of furazolidone and metronidazole for gastrointestinal infection. Histopathological examination revealed typical features consistent with FDE. The patient was managed with cessation of the offending medications and supportive treatment, leading to resolution of the lesions without recurrence. This case underscores the importance of recognizing disseminated FDE as a potential adverse effect of commonly used medications, necessitating prompt identification and appropriate management strategies.
Key words: Fixed drug eruption, disseminated, furazolidone, metronidazole, adverse drug reaction.