Year: 2024 | Month: May | Volume: 14 | Issue: 5 | Pages: 155-159
DOI: https://doi.org/10.52403/ijhsr.20240517
Chikungunya Infection: A Potential Re-Emerging Global Threat
Ipsa Singla1, Haripriya Bansal2, Tavishi Oberoi3, Sapna Batra4, Loveena Oberoi5, Babica Mohindroo6, Anuradha Malhotra7, Kamaldeep Singh8
1Junior Resident, Department of Microbiology, Government Medical College, Amritsar, INDIA
2Senior Resident, Department of Microbiology, Government Medical College, Amritsar, INDIA
3MBBS Intern, Government Medical College, Amritsar, INDIA
4Associate Professor, Department of Microbiology, Government Medical College, Amritsar, INDIA
5Professor and Head, Department of Microbiology, Government Medical College, Amritsar, INDIA
6Assistant Professor, Department of Microbiology, Government Medical College, Amritsar, INDIA
7Associate Professor, Department of Microbiology, Government Medical College, Amritsar, INDIA
8Assistant Professor, Department of Microbiology, Government Medical College, Amritsar, INDIA
Corresponding Author: Dr. Tavishi Oberoi
ABSTRACT
Background- Arboviral diseases, such as chikungunya dengue and now zika represent a problem. Epidemiology of chikungunya and dengue is well known, including its social and climatic factors associated, but only few data and reports of chikungunya are available. The clinical differentiation of chikungunya from dengue is no doubt challenging since both diseases can share clinical signs and symptoms leading to potential misdiagnosis of chikungunya in areas where dengue is endemic resulting in delayed treatment and high morbidity.
Aim & Objective- To assess seroprevalence, clinical presentations and seasonal trends of chikungunya infection in this region.
Material and method- The study was conducted in the Department of Microbiology, Government Medical College, Amritsar from January 2023 to December 2023. The serum samples were subjected to IgM antibody capture enzyme linked immunosorbent assay (MAC-ELISA) for detection of anti-chikungunya virus IgM antibodies.
Result- Overall, 52% (241/465) clinical samples were positive by MAC-ELISA. Females were more affected than males and age group >45 years was mostly affected. Fever (100%) was the primary symptom. Maximum cases were detected in the months of August to October with peak in September month. Majority of the cases were reported from rural area (94.8%).
Conclusion- In this study, seroprevalence of Chikungunya was significantly high. Though Chikungunya is a self-limiting infection, increasing morbidity by Chikungunya virus infection is affecting social and economic status of individual. Thus, a community empowerment to effectively control mosquito population by employing different mosquito control measures along with personal protection is mandatory to tackle future outbreak of the disease.
Key words: Chikungunya, Neglected disease, re-emerging, IgM antibody capture enzyme linked immunosorbent assay write relevant keywords