Year: 2024 | Month: March | Volume: 14 | Issue: 3 | Pages: 133-142
DOI: https://doi.org/10.52403/ijhsr.20240320
Prognostic Value of Anosmia in SARS-COV-2: A Case Control Study
Dr. Nishant Agrawal1, Dr. Rahul Jain2, Dr. Ajoy Sodani3
Senior Resident, Department of Neurology, Sri Aurobindo Institute of Medical Sciences, Indore
Professor & Head, Department of Neurology, Sri Aurobindo Institute of Medical Sciences, Indore
Professor, Department of Neurology, Sri Aurobindo Institute of Medical Sciences, Indore
Corresponding Author: Dr. Nishant Agrawal
ABSTRACT
Novel coronavirus disease 2019 (COVID-19) has rapidly evolved into a global pandemic and sudden onset of anosmia, has been recognized as a major clinical characteristic of the disease. Metanalysis of 107 studies suggested no objective parameter of severity of COVID-19 with anosmia is established. A study including age and gender matched 101 patients in each group was studied and patients with anosmia has strong association with D-Dimer, IL-6, Ferritin, LDH, Orf1ab gene, CT severity index. Also, better prognosis as compared to non-anosmic covid positive patients as compared to requirement of respiratory assistance. The present study is the first study to attempt to determine cut-offs of elevated levels of Inflammatory biomarkers in the prediction of requirement of respiratory assistance in SARS-CoV2 positive anosmia patients.
Key words: Anosmia, Covid-19, Inflammatory markers.