Year: 2024 | Month: October | Volume: 14 | Issue: 10 | Pages: 319-325
DOI: https://doi.org/10.52403/ijhsr.20241034
Effect of Chemotherapy on Diaphragm Mobility and Diaphragm Thickness in Breast Cancer Patients: An Observational Study
Dr. Apurva Bipin Joshi1, Dr. Abhijit Diliprao Diwate2, Dr. Arijit Kumar Das3
1Department of Cardiovascular and Respiratory Physiotherapy, 2Department of Cardiovascular and Respiratory Physiotherapy, 3Department of Cardiovascular and Respiratory Physiotherapy
DVVPF’s College of Physiotherapy, MUHS University, Ahmednagar, India.
Corresponding Author: Dr. Apurva Bipin Joshi
ABSTRACT
Background: Breast cancer being the common malignancy that affect many women nowadays and those patients with breast cancer often experience dyspnea after chemotherapy associated with the chemotherapy-induced injury of respiratory muscles and peripheral nerves. Also, Chemotherapy is known to induce diverse side effects including damage to the mitochondrial DNA.
Objective: To find out the effect of chemotherapy on diaphragm mobility and diaphragm thickness in breast cancer patients.
Materials & Method: The study was conducted with 30 diagnosed breast cancer patients who met the inclusion criteria using a cross-sectional research design. After approval of ethical clearance, informed consent was obtained from the participants. Data was collected by Ultrasonography before starting of chemotherapy and after 5 weeks of chemotherapy. Demographic data and baseline measures were recorded before starting the examination. The collected data were measured using the open Epi Instat version for Windows statistical software.
Result: In the present study of 30 patients, the mean age group was 50.23±12.31, height 157.03±5.18, weight 56±6.0. In our study, we found a result showing statistically significant changes in diaphragm mobility and diaphragm thickness in breast patients.
Conclusion: The study concludes that patients with breast cancer showed significant decline in diaphragm mobility and diaphragm thickness after administration of 5 weeks of chemotherapy.
Key words: Diaphragm mobility, Diaphragm thickness, Breast cancer, respiratory muscles, Ultrasonography.