Original Research Article
Year: 2023 | Month: June | Volume: 13 | Issue: 6 | Pages: 203-218
DOI: https://doi.org/10.52403/ijhsr.20230634
Prevalence of Hyperlipidemia in Newly Diagnosed and Uncontrolled Type-2 Diabetes Mellitus Patients Comparative to Non-diabetic Individuals
Nidhan Chandra Paul1, Probir Kumar Banjerjee2, Md. Jinnat Hossain3, Qazi Rabiul Islam3, Khokon Kumar Dutta1
1Department of Biochemistry and Molecular Biology, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj, Dhaka, Bangladesh
2Department of Gastroenterology, Sheikh Sayera Khatun Medical College, Gopalgonj, Dhaka, Bangladesh
350, Bedded Diabetes Hospital, Gopalganj, Dhaka, Bangladesh
Corresponding Author: Khokon Kumar Dutta
ABSTRACT
Objective: Diabetes increases the risk of cardiovascular disease by two to four times, with 80% of related deaths and hospitalizations due to atherosclerosis. Dyslipidemia plays a crucial role in the development of atherosclerosis and heart diseases, making it a concern for newly diagnosed and uncontrolled type-2 diabetes mellitus patients in Bangladesh. To address this, a cross-sectional study in a south-western district of Bangladesh was conducted to assess the prevalence and pattern of hyperlipidemia.
Methods: In a study of 120 participants, 83 were included in the analysis. Basic information and medical history were collected, and diabetes was diagnosed based on blood glucose levels. Lipid profiles were evaluated, and hyperlipidemia was defined as specific levels, including total cholesterol over 200 mg/dL, triglycerides over 150 mg/dL, LDL-C over 100 mg/dL, and HDL-C less than 40 mg/dL.
Results: The uncontrolled diabetic and newly diagnosed type-2 diabetes mellitus groups had a higher frequency of hypertriglyceridemia, hypercholesterolemia, hyper LDL cholesterolemia, and hypo HDL-cholesterolemia compared to the diabetic controlled and non-diabetic groups. The prevalence of high triglyceride levels was higher in females (85%) than males (76%). Gender was significantly associated with LDL-c levels (p=0.04), while the age group of 40 years or older was significantly associated with TG levels (p=0.05).
Conclusion: Dyslipidemia, including hypercholesterolemia, hypertriglyceridemia, and elevated LDLc, is a growing concern in Bangladesh. The risk is higher in people with uncontrolled or newly diagnosed type-2 diabetes. Early detection and treatment are crucial to reduce the risk of related conditions, especially cardiovascular diseases, in Bangladesh.
Key words: Type-2 diabetes mellitus, hypertriglyceridemia, LDL, physical activities, hypertension, cardiovascular diseases