Original Research Article
Year: 2022 | Month: May | Volume: 12 | Issue: 5 | Pages: 213-227
DOI: https://doi.org/10.52403/ijhsr.20220523
Standardization and Physicochemical Evaluation of the Drug Raja Elathi Chooranam - A Siddha Polyherbal Formulation
J. Manimekalai1, P. Aswini2, K. Nalina Saraswathi3, M. D. Saravana Devi4, V. Velpandian5
1PG Scholar, Post Graduate Department of Gunapadam, Government Siddha Medical College, Arumbakkam, Chennai - 600 106, Tamil Nadu, India,
2PG Scholar, Post Graduate Department of Gunapadam, Government Siddha Medical College, Arumbakkam, Chennai - 600 106, Tamil Nadu, India;
3Lecturer, Post Graduate Department of Gunapadam, Government Siddha Medical College, Arumbakkam, Chennai - 600 106, Tamil Nadu, India,
4Professor, Head of the Department, Post Graduate Department of Gunapadam, Government Siddha Medical College, Arumbakkam, Chennai- 600 106, Tamil Nadu, India.;
5Professor, Post Graduate Department of Gunapadam, Government Siddha Medical College, Arumbakkam, Chennai - 600 106, Tamil Nadu, India.
Corresponding Author: J. Manimekalai
ABSTRACT
Siddha drugs are natural products obtained from herbal, herbo-mineral, mineral and animal kingdom. Most of the Siddha medicines are effective but they have not been standardized yet. So, there be in need to progress a standardization technique. Raja Elathi Chooranam is a poly-herbal formulation mentioned in the classical Siddha literature for the medication of Menorrhagia. The aim of this study to estimate quality of Raja Elathi Chooranam by conducting physicochemical analysis, phytochemical analysis and other analytical techniques. This study was done based on Pharmacopoeial laboratory for Indian Medicine guidelines. High performance thin layer chromatography was done through CAMAG software. The organoleptic character of the sample drug justifies the solid and its aromatic and fine powder nature confirms that the formulation is of good quality. The results obtained after phytochemical analysis of test drug showed 2.427 ± 0.4839 % of Loss on drying at 105°C, 9.633 ± 0.7506% of Total Ash, 0.054 ± 0.01652 % of Acid insoluble ash etc. The pH value of the drug 6.5 which is indicates it is weakly acidic. The results obtained after preliminary phytochemical analysis confirmed the presence of alkaloids, flavonoids, steroids, triterpenoids, coumarin, phenols, tannins, saponins and sugar. Biochemical analysis of the test drug reveals the presence of Carbonates, Chlorides, Sulphates and Phosphates. The test drug is devoid of microbial contamination, heavy metals and pesticide residues were below quantification limit. From the result we infer that the drug is of standard quality and shall be used as reference in pharmacopoeia standards.
Key words: Standardization, Raja Elathi Chooranam, Poly herbal, Siddha, Physicochemical analysis, phytochemical analysis.