Case Report
Year: 2022 | Month: March | Volume: 12 | Issue: 3 | Pages: 314-319
DOI: https://doi.org/10.52403/ijhsr.20220342
Neuroleptic Malignant Syndrome: Catch Me If You Can; A Case Report
Maryam Adam Ali1, Noora Adam Ali2, Khurram Sarfaraz3, Mustafa Mohamed Hammad4, Naser Mohamad Ali Mansoor5
1Trainee Doctor, Department of Medicine, Salmaniya Medical Complex (SMC), Kingdom of Bahrain
2,4Intern, SMC, Kingdom of Bahrain
3,5Chief Resident, Department of Emergency, SMC, Kingdom of Bahrain
Corresponding Author: Khurram Sarfaraz
ABSTRACT
Neuroleptic Malignant Syndrome (NMS) is a relatively rare adverse reaction to neuroleptic medications. It is characterized by a constellation of findings that usually occur concurrently. These include vital instability, fever, elevated creatinine kinase, encephalopathy, and muscle rigidity. Having a high index of suspicion can reduce mortality and long-term complications by having a broad differential diagnosis when facing a patient with these symptoms, particularly if they are on antipsychotic medications. Withdrawal of the offending medication and supportive therapy are the most important initial steps in patient management.
In this case report, we discuss the case of a 95-year-old male on quetiapine and memantine with a 2-day history of fever, rigidity, cough, and reduced activity after increasing the dose of quetiapine three days prior to his presentation.
Key words: Neuroleptic malignant syndrome, Antipsychotics, Neuroleptics, Muscle rigidity Creatinine Kinase.