Original Research Article
Year: 2022 | Month: March | Volume: 12 | Issue: 3 | Pages: 18-22
DOI: https://doi.org/10.52403/ijhsr.20220303
A Study of Hematological Profile in Dengue Fever in a Tertiary Care Hospital
Supriya Karmakar1, Nanda Patil2
1Tutor of Pathology, Krishna Institute of Medical Sciences Deemed to be University, Karad.
2Professor of Pathology, Krishna Institute of Medical Sciences Deemed to be University, Karad.
Corresponding Author: Supriya Karmakar
ABSTRACT
Background: Dengue fever and dengue hemorrhagic fever has emerged as a global public health problem in recent decades.(1) It is an acute febrile illness with symptoms of sudden onset of fever, headache, bodyache, generalized weakness, retro-orbital pain and rash.(2) Its diagnosis is based on clinical and laboratory data. Clinical symptoms and signs along with laboratory tests i.e. both non-specific [blood count, platelet count, prothrombin time (PT)] and specific tests (viral isolation tests and serology for antibody examination) are evaluated for diagnosis.(3,4)
Aim: To study haematological profile in patients of dengue fever.
Objective: To correlate haematological parameters with clinical details.
Methods: The present study is a two year hospital based prospective study of all the haematological parameters in patients diagnosed serologically positive as dengue fever in tertiary care centre from June 2019 to May 2021, which includes 210 cases.
Results: 104 cases (49.5 %) were in the 2nd decade of life, which was the most common age group. There were 115 (54.7 %) males and 95 (45.2%) females. The most common presenting complaint was fever (185 cases). 98 cases (46.6%) were noted with hemoglobin ranging from 12-15 gm/dl and with hematocrit levels ranging from 40-49%. 128 cases (60.9 %) had TLC within normal limit. Maximum number of patients i.e. 87 cases (41.4 %) had platelet count with moderate thrombocytopenia. In DHF and DSS cases, 18 (72%) cases showed moderate thrombocytopenia. According to bleeding manifestations, petechiae was noted in 18 cases, hematemesis in 8 cases whereas 3 cases presented with melena.MPV and PDW in thrombocytopenic patients was found to be significantly higher than in non-thrombocytopenic patients.
Conclusion: Hematocrit (HCT) and platelet count monitoring is useful to determine therapeutic intervention in case of dengue fever.
Key words: Dengue fever, haematological profile, clinical correlation.