Original Research Article
Year: 2021 | Month: September | Volume: 11 | Issue: 9 | Pages: 137-141
DOI: https://doi.org/10.52403/ijhsr.20210921
Prevalence of Gastric Cancer Associated with the Epstein-Barr Virus at Brazzaville Chu
Fidele Mambouene1, Anicet Boumba2, Fabien Mouamba3, Valere Belle Mbou4, Dimitry Moudiongui5, Deby Gassaye6, Jean Felix Peko7
1PhD Student Pending Defense in Service at the Pathological Anatomy Laboratory of the University Hospital of Brazzaville
2Oncology, Virology and Molecular Biology, General Hospital of Loandjili Pointe Noire
3Pathologist and Assistant at the Faculty of Medicine, Pathological Anatomy Laboratory of the University Hospital of Brazzaville
4Pathologist and Hospital Practitioner, Poitier Hospital France
5PhD Student Pending Defense in Service at the Pathological Anatomy Laboratory of the University Hospital of Brazzaville
6Hepato Gastroenterologist in the Gastroenterology Department of the University Hospital of Brazzaville,
7Anatomopathologist, Professor at the Faculty of Medicine, Head of Service, Pathological Anatomy Laboratory of the University Hospital of Brazzaville
Corresponding Author: Fidele Mambouene
ABSTRACT
Introduction: Several studies have shown an association between infection with Epstein-Barr virus (EBV) and the occurrence of many cancers in humans, including certain gastric carcinomas (GC). Indeed, recent studies have reported that 10% of CGs are associated with EBV.
Materials and Methods: Samples of gastric carcinomatous tissues (biopsies and surgical specimens) were analyzed by PCR for the detection of EBV. Samples were collected retrospectively between January 2008 and December 2018.
Results: during this period, 52 samples were analyzed. PCR results show the EBV infection rate to be 3.8%.
Conclusion: The results obtained during this preliminary study confirm the association of EBV in 3.8% of CG cases, which is consistent with the data in the literature.
Key words: EBV, gastric carcinoma, PCR.