Case Report
Year: 2021 | Month: January | Volume: 11 | Issue: 1 | Pages: 107-110
MRI Features of Multiple System Atrophy - A Case Report
Sujoy Mani1, Ojaswi Khandediya2, Priti Kapoor3
1JR-1 Radiodiagnosis, MGM Medical College and Hospital, Sector-1, Kamothe, Navi Mumbai-410209.
2JR-3 Radiodiagnosis, MGM Medical College and Hospital, Sector-1, Kamothe, Navi Mumbai-410209.
3Head of Department Radiodiagnosis, MGM Medical College and Hospital, Sector-1, Kamothe, Navi Mumbai-410209
Corresponding Author: Sujoy Mani
ABSTRACT
Multiple system atrophy (MSA) is a synucleinopathy, which is characterized by combined manifestations of Parkinsonian, cerebellar and autonomic features. It is broadly subdivided into two main groups- Parkinsonian MSA (MSA-P) and cerebellar MSA (MSA-C). Magnetic resonance imaging (MRI) of the brain is an essential tool in making a confident diagnosis of this condition. The clinical phenotype usually shows crossover and is at times very complex. On the other hand, Magnetic Resonance Imaging of the Brain may show many characteristic features, such as the 'hot cross bun' sign. This is a cruciform hyperintensity seen at the level of pons in axial T2-weighted MRI images. This sign is characteristically seen in patients with MSA-C. This case report deals with a patient with characteristic brain MRI features of MSA-C type.
Key words: Multiple system atrophy, Hot-cross bun sign, Magnetic Resonance Imaging, Olivopontocerebellar degeneration