Original Research Article
Year: 2021 | Month: November | Volume: 11 | Issue: 11 | Pages: 203-207
DOI: https://doi.org/10.52403/ijhsr.20211126
Effect of ROX Index on the Ventilator Free Days in High Flow Nasal Oxygen and Early Invasive Mechanical Ventilation in Adult COVID -19 Patients
Joslita Rebello1, Monisha B. J. Neelankavil2, Ananth Srikrishna Somayaji3
1Post Graduate, Anaesthesiology, Father Muller Medical College Mangalore
2Senior Resident, Anaesthesiology, Father Muller Medical College, Mangalore
3Senior Resident, Father Muller Medical College, Mangalore
Corresponding Author: Joslita Rebello
ABSTRACT
Background: High flow nasal oxygen (HFNO) is used as an alternative respiratory support in hypoxemic respiratory failure in COVID -19. However the use of HFNO was associated with a lower risk of invasive mechanical ventilation and duration of stay in ICU. This study is aimed at comparing ventilator free days and duration of ICU stay between early mechanical ventilation and HFNO use in COVID -19 to predict the clinical outcome.
Methods: We performed a unicentre prospective observational analytical study on subjects with respiratory failure due to COVID -19 comparing effect of ROX index on ventilator free days with use of HFNO therapy and mechanical ventilation on first day of intensive care unit admission. Each group had 20 subjects. Clinical outcome was measured in terms of ventilator free days between two groups. Standard statistical comparisons were used to compare the length of icu stay as secondary outcome. APACHE II and SOFA sores were compared and analysed between two groups.
Results: 40 adult subjects critically ill due to COVID -19 were included in the study with 20 in each group. Subjects in HFNO group had higher ventilator free days than those were put on early mechanical ventilation with significant difference. Whereas the duration of icu stay was prolonged in HFNO group but there was no significant statistical difference.
Conclusions: In this prospective study HFNO had better clinical outcome in terms of ventilator free days compared to early mechanical ventilation. Duration of stay in ICU had no difference.
Key words: Ventilator free days, HFNO, number of days in ICU, ROX index, APACHE II, SOFA score.