Review Article
Year: 2020 | Month: December | Volume: 10 | Issue: 12 | Pages: 294-301
Advancement of Standardization Process of Traditional Pharmaceuticals: A Review
Udahapuvida BMMSHK1, Weerasooriya WMB2, Liyanage JA3
1Temporary Lecturer, Ayurveda Medical Education Unit, Gampaha Wickramarachchi Ayurveda Institute, Sri Lanka
2Senior Lecturer, Department of Dravyaguna, Gampaha Wickramarachchi Ayurveda Institute, Sri Lanka
3Senior Professor, Department of Chemistry, Faculty of Science, University of Kelaniya, Sri Lanka
Corresponding Author: Weerasooriya WMB
ABSTRACT
Around 75% - 80% of the world population is depending on traditional medicine and natural medicine for their primary health care needs. In the present era people looking towards traditional medicine for their health problems due to long term acceptability and also they believe that herbal medicine is safe and free from adverse effects. The development of quality control protocols for herbal medicines is an essential operation to ensure the safety and efficacy of herbal pharmaceuticals. The present review was focused to elaborate the evolution and advancement of application of quality concept and standardization of traditional pharmaceutical industry in past two decades. Peer reviewed articles and authentic texts were reviewed and compiled. Botanical parameters, physiochemical parameters, pharmacological parameters, toxicological parameters and chromatographic techniques had been introduced by WHO for Standardization of traditional pharmaceuticals. Macroscopic, microscopic, physiochemical, microbial quality, spectrophotometric had chromatographic techniques had been widely evolved to standardize herbal pharmaceuticals. At present, novel and advanced techniques had been popularized for standardization of herbal pharmaceuticals such as fluorescence quenching, combinations of spectrophotometric and chromatographic methods, DNA and chemical finger print methods. The results of this review revealed that the advancement of quality concept and standardization of traditional or herbal pharmaceuticals have been evolved with integration of continuously developed science based technologies.
Key words: Traditional medicine, Quality control, Standardization.