Original Research Article
Year: 2020 | Month: December | Volume: 10 | Issue: 12 | Pages: 1-7
Study of Hematological Profile in Chronic Renal Failure Patients on Hemodialysis in a Tertiary Care Hospital
Ruchi Khadayate1, Piyush Sahu2, Shilpi Sahu3, Siddhi Karale4
1,4Third Year Post Graduate Student, 2Assistant Professor, 3Professor & Head of Department, MGM Medical College & Hospital, Kamothe, Navi Mumbai-410209, Maharashtra
Corresponding Author: Ruchi Khadayate
ABSTRACT
Background: Chronic Kidney Disease is a cause of high morbidity and mortality in developing nations like India. The various hematological parameters and their correlation to different stages of CKD help assess the severity, prognosis and outcome of these patients.
Methods: A hospital based cross-sectional observational study was done to detect the prevalence of haematological abnormalities, correlation of anaemia, typing of anemia with CKD stages(stages 3 to 5) of the patients were included in this study. Presence of anaemia (Hb%, MCV, peripheral smear), RDW, thrombocytopenia, leucocyte count, differential count in different stages of CKD were studied.
Result: The 96.8%subjects in the study group are anemic with normocytic and normochromic findings on peripheral smear. 57.3% patients had High TLC but no significant association was established with High TLC with increasing stage of CKD. MCV and Platelets were within normal limits with only slight variation. Increased RDW has a positive correlation with CKD.
Conclusion:The CKD patients have various changes in the blood parameters especially anemia and iron studies should be carried out so that treatment for that should be started and improve the quality of life in CKD patients.
Key words: Anaemia in CKD, Chronic kidney disease, Haematological abnormalities in CKD, Iron deficiency anaemia, Thrombocytopenia.