Case Report
Year: 2020 | Month: November | Volume: 10 | Issue: 11 | Pages: 220-224
Myoepithelial Carcinoma of Intra-Oral Minor Salivary Glands Mimicking a Sarcoma - A Rare Case
Kumar Nilesh1, S.R. Kanetkar2, N. J. Patil3, Jyoti Tele4, Sucheta Bansal5
1Professor and Head, Department of Oral and Maxillofacial Surgery, SDS, Krishna Institute of Medical Sciences, Deemed to be University, Karad 411510, Maharashtra, India.
2Professor and Head, Department of Pathology, Krishna Institute of Medical Sciences, Deemed to be University, Karad 411510, Maharashtra, India.
3Professor, Department of Pathology, Krishna Institute of Medical Sciences, Deemed to be University, Karad 411510, Maharashtra, India.
4Assistant Professor, Department of Pathology, Krishna Institute of Medical Sciences, Deemed to be University, Karad 411510,Maharashtra, India.
5Tutor, Department of Pathology, Krishna Institute of Medical Sciences, Deemed to be University, Karad 411510, Maharashtra, India.
Corresponding Author: Sucheta Bansal
ABSTRACT
Background: Myoepithelial tumors are rare and account for less than 1% of all salivary gland tumors, of which majority are benign and only a few cases of malignant myoepitheliomas have been reported till date. A malignant myoepithelioma may arise de novo or develop within a preexisting pleomorphic adenoma or benign myoepithelioma.
Case report: We report a case of 60 year old male with complaints of pain and swelling over right side of mouth in upper jaw region. Intra oral examination revealed, a soft pedunculated lesion extending from the hard palate. Microscopically, the lesion was composed of fascicles of malignant spindle cells, mimicking a sarcoma. On IHC, tumor cells showed positivity for SMA, p63 and S-100 and final diagnosis of Myoepithelial carcinoma was reached.
Conclusion: The diagnosis of myoepithelial carcinoma due to its rarity and morphological heterogeneity can be challenging. Therefore a high index of suspicion and confirmation via immunohistochemical markers is essential.
Key words: Myoepithelial carcinoma, minor salivary gland tumor, oral malignancy.