Year: 2019 | Month: April | Volume: 9 | Issue: 4 | Pages: 286-293
Kashmiri Diet and Gastric Carcinoma Epidemiology and Risk Factors: A Review
Maeena Naman Shafiee1, Dr. Sheikh Mohd Saleem2
1PhD. Research Scholar, Dept. of Food Science and Technology, University of Kashmir, Srinagar, J&K, India.
2Senior Resident, Department of Community Medicine, Government Medical College, Srinagar, J&K, India.
Corresponding Author: Maeena Naman Shafiee
Kashmiri population has distinct dietary habits owing to the long winter spells prevalent in the valley which has accustomed the population to preserve the food in the form of smoked, pickled and dried foods. These peculiar dietary habits contribute to the intake of many N-nitroso compounds (NOCs) which are responsible for DNA damage, Cytotoxicity, gene mutation, DNA methylation, and unscheduled DNA synthesis. At the molecular level, these changes are responsible for the pathogenesis of cancer. This paper presents a review of the relation between the Kashmiri diet and gastric carcinomas, highly prevalent in the valley. This study creates an initial study base and enlists the number of potential factors responsible for the alarming rate of gastric carcinoma in the valley.
Key words: Kashmir, Kashmiri diet, gastric cancer, N-Nitrosodimethylamine, dietary habits