Original Research Article
Year: 2019 | Month: February | Volume: 9 | Issue: 2 | Pages: 211-225
Neuro-Cognition in First Degree Relatives of Patients with Schizophrenia and Mania with Psychotic Symptoms: A Comparative Study
Vikas Kumar1, Dr. Basudev Das2, Dr. Deyashini Lahiri3
1Clinical Psychologist, Sri Sri University, Cuttack, Odisha.
2Professor of Psychiatry, Central Institute of Psychiatry, Ranchi Jharkhand.
3Assistant Professor of Clinical Psychology, Central Institute of Psychiatry, Ranchi, Jharkhand.
Corresponding Author: Vikas Kumar
Non-affective psychosis refers to psychosis not related to emotions or mood. Affective psychosis is a psychological disorder where people experience a loss of contact with reality and experience where mood disturbances are the primary cause. The focus has been shifted to the first degree relatives of these populations to prevent the disorder at the earliest. So, the first degree relatives are known to be high risk population with genetic vulnerability. These two psychotic disorders (schizophrenia & mania with psychotic symptoms) show various impairments in various field but these impairments are present to define these disorders, unaffected relatives of these two disorders for different areas like social, cognitive, neurocognitive and social functioning. Cognitive dysfunction as trait marker nearly established in affective and non- affective population. Aim of this study to assess neurocognition and social functioning in first degree relatives of patients with schizophrenia and mania with psychotic symptoms. Sample consisted of 30 first degree relatives (FDR) of patients with schizophrenia and mania with psychotic symptoms and 15 normal healthy control. After the initial screening by the clinical assessments, based on their amenability for the interview, tool for the assessment of neurocognition (RAVLT, DST, TMT) and socio-occupational functioning (SOFS) were applied on all three groups. The study found that first degree relatives of patients with schizophrenia and mania with psychotic symptoms groups were found higher in reaction time in trail making on measure of neurocognition compared to healthy controls.
Key words: Affective and Non-affective psychosis, FDR, Neurocognition, Social functioning.