International Journal of Health Sciences and Research

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Original Research Article

Year: 2019 | Month: January | Volume: 9 | Issue: 1 | Pages: 28-35

Evaluation of Anti-Microbial Activity of Ziziphus mauritiana (Ber), Ocimum sanctum (Tulsi) and Ficus religiosa (Peepal) on Staphylococcus aureus Strains Isolated from Environment of Various ICUs

Arth Nath Dube1, Saami Nazim Shahbazker2, Mohammad Nasim3, Dr. H. Kar4

1Resident, Medical Microbiology, MGM Medical College, Kamothe, Navi Mumbai
2Resident Medical Microbiology, MGM Medical College, Kamothe, Navi Mumbai
3Resident Medical Microbiology, MGM Medical College, Kamothe, Navi Mumbai
4Assistant Professor, Microbiology Dept., MGM Medical College, Kamothe, Navi Mumbai

Corresponding Author: Arth Nath Dube


Acetone and Diethyl ether leaf extracts of 3 medicinal plants traditionally used in medicine were studied for their antimicrobial activity against. Total of 270 samples (240 swabs and 30 expose plates) were collected out of which 39 (14.44%) Staphylococcus aureus strains were isolated from different instruments and surfaces of various ICUs. The antimicrobial activity of plant extracts was determined by using disc diffusion method. The plant extracts showed varied levels of antimicrobial activity against these S. aureus isolates. Acetonic Extracts of Ocimum sanctum (Tulsi) showed good activity against most of the isolates whereas the extracts of Ziziphus mauritiana (ber) showed moderate activity against most of the isolates. The plant extracts showed variable initial sensitive pattern values against these S. aureus isolates being maximum zone size for O. santum (16.5mm) followed by Z. mauritiana (13.5mm) for acetonic extract and for Diethyl ether extract maximum zone size was for Z. mauritiana (14.7mm) followed by O. sanctum (13.5mm). The present study thus suggests the use of these medicinal plants in the treatment of various diseases caused by drug resistant S. aureus strains.

Key words: Medicinal plants, Antimicrobial activity, Staphylococcus aureus, MDR (multi-drug resistance), Nosocomial infections

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