International Journal of Health Sciences and Research

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Original Research Article

Year: 2018 | Month: August | Volume: 8 | Issue: 8 | Pages: 52-55

Emergence of Multidrug Resistant Pseudomonas Aeruginosa in a Tertiary Care Center

Suneet Yadav1, R. Sujatha2, Deepak S3

1Tutor, 2Prof. and Head, 3Pg student, Department of Microbiology, Rama Medical College Hospital and Research Center Kanpur (India)

Corresponding Author: Dr. R. Sujatha


The worldwide emergence of multi-drug resistant bacterial strains in hospitals and community continues to be a problem of due scientific concern, especially infections caused by Pseudomonas species. This study was carried out to determine the multidrug resistant pattern of P.aeruginosa, among the clinical isolates at a tertiary care hospital in Kanpur.
Methods: Total 50 P. aeruginosa were isolated from different clinical samples of a tertiary care hospital during Jun 2016 to Dec 2016. Bacterial isolates were identified by standard microbiological tests and antimicrobial resistance pattern were determined by CLSI guidelines.
Results: Among 50 P. Aeruginosa,(70%) strains were isolated from pus followed by sputum (10%), bronchial washing (20%). Most of the organism was isolated from advance age and in male patients. Out of 50 P. Aeruginosa isolates, 20 (40%) were resistant to piperacillin tazobactam, tobramycin and levofloxacin, 30 (60 %) were resistant to ceftazidime, cefepime and meropenem, 10 (20%) were resistant to imipenem and amikacin, 25 (50%) were resistant to ciprofloxacin.
Conclusion: There has been rapid emergence of MDR P.aeruginosa in recent times which is an important concern for clinicians who treat these infections. Therefore restriction of ‘selected antibiotic usage’ and infection control policies must be undertaken to combat the rapid emergence of MDR P.aeruginosa. P.aeruginosa showed highest resistance to piperacillin tazobactam, tobramycin and levofloxacin and minimum resistance to imipenem and amikacin.

Key words: Multidrug resistance, P. aeruginosa, Piperacillin tazobactam..

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