Original Research Article
Year: 2018 | Month: August | Volume: 8 | Issue: 8 | Pages: 226-230
Evaluation of In-Vitro Antidiabetic Activity of Gardenia Latifolia Ait
K.Tamilselvi1, S.P.Ananad1, A.Doss2
1Department of Botany, National College, Trichy
2PG & Research Department of Botany, V.O.Chidambaram College, Thoothukudi
Corresponding Author: A.Doss
The aim of the present work was to evaluate the antidiabetic activity of ethanol and aqueous extract of leaves of Gardenia latifolia. The samples were studied for their effect on inhibition of alpha amylase, alpha glucosidase and glucose transport across yeast cells. The significant results were observed in the crude extracts. The α-glucosidse & α-amylase inhibition was in a dose dependent manner and glucose transport differs with the sample and glucose concentration. From the results of the study, it is inferred that, Gardenia latifolia leaves possesses antidiabetic activity. However, these effects need to be confirmed using in vivo models and clinical trials for its effective utilization as therapeutic agents.
Key words: Inhibitors, Hyperglycemia, acarbose, medicinal plants, folk medicine.