Original Research Article
Year: 2018 | Month: May | Volume: 8 | Issue: 5 | Pages: 62-66
Comparative Evaluation of Salivary Flow Rate, Ph, Buffering Capacity, Total Protein and Albumin Levels in Chronic Periodontitis Patients: A Clinico-Biochemical Study
Dr. Yugantar N. Wakde1, Dr. Asmita Singh2, Dr. Ananya Vikram Singh3
1Tutor Department of Biochemistry, Raipur Institute of Medical Sciences, Bhansoj road, RAIPUR, Chhattisgarh.
2PG student, Department of Periodontology, Rungta College of Dental Sciences and Research, Kohka-kurud Road, Bhilai, Chhattisgarh.
3Dental Consultant, DENTIQUE, Near Bhilai Nursing Home, Bhilai, Chhattisgarh
Corresponding Author: Dr. Yugantar N. Wakde
Aim and objectives: This study was designed to compare the total protein concentration, albumin, flow rate, pH, buffering capacity of saliva in healthy subjects, patients with gingivitis and chronic periodontitis.
Materials and methods: A total of 60 patients were selected and were divided into three groups (20 subjects each) as controls, gingivitis and chronic periodontitis. Plaque index, gingival index, modified sulcular bleeding index, probing pocket depth and clinical attachment level were recorded. The unstimulated whole saliva was collected from patients and flow rate was noted down during collection of the sample. Estimation of total salivary protein and albumin was performed by colorimetric method. The pH estimation was done using pH meter and buffering capacity was analysed with the titration method.
Results and Conclusion: The results of this study showed significant rise in salivary total protein and albumin concentration in gingivitis and chronic periodontitis patients whereas pH, buffer capacity and flow rate did not show any significant changes. Thus, salivary total protein and albumin concentration may serve as an important biochemical parameter of inflammation of the periodontium.
Key words: Saliva, salivary protein, gingivitis, periodontitis.