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Original Research Article

Year: 2018 | Month: May | Volume: 8 | Issue: 5 | Pages: 28-35

An Evaluation of Nerve Conduction Studies and Clinical Parameters in Patients with Symptomatic Lumbar Intervertebral Disc Herniation Treated With Gabapentin

Dr. Nilabh1, Dr. Beena2, Dr. Naveen Malhotra3

1Postgraduate, Department of Physiology, Pt. B.D.S P.G.I.M.S, Rohtak (Haryana),
2Professor, Department of Physiology Pt. B.D.S P.G.I.M.S, Rohtak (Haryana),
3Professor, Department of Pain and Anaesthesiology, Pt. B.D.S P.G.I.M.S, Rohtak (Haryana),

Corresponding Author: Dr. Nilabh


Background: Prolapsed Intervertebral disc herniation is the most common cause of lumbar pain and radiculopathy. Diagnosis is usually made by clinical parameters, MRI, electromyography and nerve conduction study.
Objective: This research paper aimed to evaluate nerve conduction study and clinical parameters in patients with symptomatic lumbar intervertebral disc herniation treated by Gabapentin.
Methodology: Thirty patients of either sex, in the age group of 18-50 years, newly diagnosed with history, physical examination and pain pattern consistent with low back ache and prolapsed intervertebral disc were included in the study. Nerve conduction study of tibial, peroneal and sural nerve was done in both lower limbs. Pain was assessed using Numeric Rating Scale (NRS 0-10), patient disability was assessed with Oswestry Disability Index (ODI) before treatment and after 2 and 6 weeks respectively. Patient satisfaction was assessed using four point scale after 2 and 6 weeks respectively. The quantitative data has been analyzed using (SPSS) version 20.0
Results: Improvement in pain in all patients following treatment with Gabapentin. The clinical parameters were statistically significant viz Numeric Rating Scale and Oswestry Disability Index. Patient satisfaction improved significantly. In our study, the variation in amplitude, latency and conduction velocity all were found to be statistically significant at the end of 6 weeks.
Conclusion: The clinical parameters and nerve conduction study both improved in patients with lumbar intervertebral disc herniation after treatment with gabapentin.

Key words: Prolapsed intervertebral disc herniation, gabapentin, numeric rating scale, nerve conduction study, Oswestry disability index, patient satisfaction.

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