Year: 2018 | Month: May | Volume: 8 | Issue: 5 | Pages: 287-291
First Line Drug Resistance Study in Pulmonary Tuberculosis Patients from Mayurbhanj District of Odisha, India
Prakasini Satapathy1, Bairagi C Mallick2, Dasarathi Das3
1Senior Research Fellow, ICMR, Regional Medical Research centre, Indian Council of Medical Research, Bhubaneswar -751023, India and
PhD Student, Department of Biotechnology, Ravenshaw University, Cuttack-753003, Odisha, India
2Assistant professor, Department of Chemistry, Ravenshaw University, Cuttack-753003, Odisha, India
3Scientist-E, Regional Medical Research centre, Indian Council of Medical Research, Bhubaneswar -751023.
The study was conducted at Mayurbhanj district of Odisha, India, among pulmonary tuberculosis (PTB) patients to determine the resistance pattern to first-line drugs. Sputum samples were collected from 56 (42 new and 14 previously treated) patients and were tested at Regional Medical Research Centre, Bhubaneswar. Resistance to any anti-tubercular drug was observed to be 2.18% among new cases and 7.14% among previously treated patients, while multidrug-resistant tuberculosis (MDR-TB) was found to be 0% in new as well as in previously treated cases. The study reports an unchanged low level of MDR-TB prevalence among new cases in the district over a decade. Such a low level of resistance may be due to good adherence to the basic DOTS plus strategy and limited use of TB drugs outside the ongoing program.
Key words:Drug resistance, Mayurbhanj, MDR-TB.