International Journal of Health Sciences and Research

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Original Research Article

Year: 2018 | Month: January | Volume: 8 | Issue: 1 | Pages: 54-59

Optimization of Environmental Parameters for Trichophyton rubrum Growth and its Antigen Production

G.L. Aruna1, Ramalingappa2

1Department of Microbiology, Government Science College, Chitradurga- 577501. Karnataka, India
2Department of Studies and Research in Microbiology, Davangere University, Davangere. Karnataka, India

Corresponding Author: Ramalingappa


Trichophyton rubrum is a dermatophyte cause dermatophytosis in humans and animals worldwide. It is the most prevalent form of dermatophyte. In the present study, the effect of different environmental factors on growth and antigen production of T. rubrum was studied. The optimum temperature and pH for the growth and antigen production of T. rubrum was found to be 32o C and 7 respectively. Among four media used in this study, SDA1 and SDB2 were found to be most suitable for T. rubrum’s growth and antigen production respectively. The optimal incubation time was found to be 30 days. Light intensity and aeration were induced both growth and antigen production. This study may help in understanding of the pathogenicity and host immune responses against T. rubrum.

Key words: Trichophyton rubrum, dermatophyte, colony diameter, anthropophilic and Optimization

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