Original Research Article
Year: 2018 | Month: December | Volume: 8 | Issue: 12 | Pages: 18-24
Clinico-Hematological Profile of Dengue Fever during the Monsoon of 2016 in Central Kerala
Kavitha R Nair1, Dr Seema Oommen2, Dr Vidya Pai3
1Tutor, Department of Microbiology, Pushpagiri Institute of Medical Sciences and Research Centre, Tiruvalla, Kerala.
2Professor and Head, Department of Microbiology, Pushpagiri Institute of Medical Sciences and Research Centre, Tiruvalla, Kerala.
3Professor and Head, Department of Microbiology, Yenepoya Medical College, Yenepoya University, Mangalore, Karnataka.
Corresponding Author: Dr Seema Oommen
Background and objective: Dengue is one of the most common mosquito-borne viral infection involving newer areas, newer populations and increasing in magnitude after each epidemic in India. This study is aimed to study the clinico-hematological profile of patients with dengue fever during the monsoon of 2016 in a tertiary care teaching hospital.
Materials and methods: A prospective study conducted in a tertiary care centre in Tiruvalla, Kerala from May 2016 to August 2016.A total of 236 adult patients who were positive for NS1 Antigen were further analyzed for their biochemical, hematological and clinical profiles.
Result: Out of 236, 183(77.5%) were diagnosed as primary dengue and 53 (22.5%) as secondary dengue infection. Common clinical symptoms were fever (100%), generalized body ache (53%), headache (42%), vomiting (22%), and abdominal pain (10%). Thrombocytopenia, leucopoenia and elevated liver enzymes were observed. All patients improved clinically and showed an improvement in their biochemical and hematological parameters. Case fatality among these patients was nil.
Conclusion: Most common form of clinical presentation in our study was primary dengue. Presence of thrombocytopenia and elevated liver enzymes are more indicative of a secondary infection.
Key words: Dengue, clinical profile, thrombocytopenia