Original Research Article
Year: 2018 | Month: December | Volume: 8 | Issue: 12 | Pages: 1-8
Parental Factors Associated with Pregnancy Outcome With Reference to Spontaneous Abortion
Riddhi Thaker1, Hina Oza2, Vinita Verma1, Sunil Kumar1
1Div. of Reproductive & Cytotoxicology, ICMR- National Institute of Occupational Health,
Ahmedabad-380016, Gujarat, India.
2Department of Obstetrics and Gynecology, Civil Hospital, Ahmedabad-380016, India
Corresponding Author: Sunil Kumar
Objective: To assess the role of environmental, occupational and lifestyle factors among women with history of spontaneous abortion (SAb Cases) with respect to women without such history (bearing child - Controls).
Methods: A total of 406 (203 SAb and equal number of control subjects) were enrolled from Gynecology department, Civil hospital, Ahmedabad and personal demographic information, medical, occupational, lifestyle and reproductive history especially details of number of SAb, duration of last SAb, number of child etc. were collected on predesigned proforma.
Results: The mean BMI of SAb subjects and their partners was significantly higher as compared to BMI of control group. Area of residence appeared to have no impact in the pregnancy outcome. More number of women with SAb was employed as compared to controls. With respect to lifestyle habits among women, it was found that the proportion of chewers (mixture containing tobacco or areca nut as main compound) were more in SAb subjects as compared to control, this difference was statistically significant. With regards to impact of paternal lifestyle factors on spontaneous abortion, it was also noted that number of male subjects with habit of tobacco chewing or smoking or alcohol consumption was higher in SAb case group as compared to control group (NS). The results of logistic regression analysis indicated that the BMI of female subjects was significantly associated with risk of SAb. One unit elevation in the BMI increases the risk of SAb by 1.093 times (OR-1.093, 95% CI-1.026 to 1.161). Also, working women were at more risk for SAb (OR-1.86%, 95% CI-1.041 to 3.355).
Conclusion: The study indicated that working women, higher BMI and women with tobacco chewing habits have significant risk of SAb than housewives, normal BMI and women without habit of tobacco chewing. No such significant impact of paternal exposure was found with respect to risk of spontaneous abortion.
Key words: Spontaneous abortion, Lifestyle, Occupation, Area of residence, BMI, Tobacco chewing.