Original Research Article
Year: 2018 | Month: November | Volume: 8 | Issue: 11 | Pages: 75-81
Spectrum of Lesions in Lymph Nodes-A Cytological Study
Dr. Prabhakar Patro1, Dr. Priyanka Lad2, Dr. Hoogar M.B.3, Dr. Reeta Dhar4, Dr Shilpi Sahu5, Dr Mithila K. B.6, Dr. Vaidehee Naik7
2,6,7Final year Post-graduate Students, 1,3Associate Professors, 4Professor,
5Professor and Head of Department of Pathology,
MGM Medical College, Kamothe, Navi Mumbai
Corresponding Author: Dr. Priyanka Lad
Introduction: Lymph nodes are common sites of clinical presentation of many of the manifestations non-neoplastic and neoplastic diseases. Fine needle aspiration cytology (FNAC) a simple relatively non-invasive procedure which can be employed in diagnosis of superficial lesions of the body.
Aim: To study cytomorphological features of various lymph node lesions- non-neoplastic and neoplastic-by fine needle aspiration of enlarged lymph nodes.
Methods: The present prospective study to analyse the cytomorphological features of pathological lesions lymph nodes by FNAC is conducted over a period of one year. The study included all the patients of both sexes with age ranging from one to 70 years who presented with clinical features of lymphadenopathy.
Results: Out of a total 330 patients with lymphadenopathy subjected to FNAC, the most common site was cervical group of lymph nodes (74.24%) which showed female preponderance (62.42%).Cytomorphology was diagnostic of tuberculous lymphadenitis (32.12%), followed by reactive lymphadenitis(25.45%), granulomatous lymphadenitis (23.33%) and acute suppurative lymphadenitis(3.63%) and metastatic malignant lesions (3.33%) with lymphoproliferative lesions of undetermined significance (0.90%) while neoplastic lesions such as non-Hodgkin’s lymphoma (0.30%).
Conclusion: FNAC is a simple, safe, reliable, and inexpensive method that could be employed in cytological study and early detection of inflammatory, reactive and neoplastic conditions leading to clinical lymphadenopathy.
Key words: Fine Needle Aspiration Cytology (FNAC), Lymphadenopathy, reactive lymphadenitis, metastatic lesions, tuberculous lymphadenitis