International Journal of Health Sciences and Research

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Original Research Article

Year: 2017 | Month: Aug | Volume: 7 | Issue: 8 | Pages: 142-149

Study of Serum Homocysteine and Lipid Profile Parameters in Patients of Chronic Renal Failure

Dr. Anurag Kesarwani1, Dr. Shilpa B. Asegaonkar2, Mr. Apurva Jha3

1Assistant Professor, Department of Biochemistry, Raipur Institute of Medical Sciences, Raipur
2Associate Professor, Department of Biochemistry, GMC, Aurangabad
3Tutor, Department of Biochemistry, Raipur Institute of Medical Sciences, Raipur

Corresponding Author: Dr. Anurag Kesarwani


Objective: The aim of the study was to evaluate the serum homocysteine level and correlate it with lipid profile in chronic renal failure patients.
Study Design: Cross-sectional study
Methods: Total 150 individuals comprising of male & female age group of 18-70 years were studied between Dec 2012- Jan 2014. They are divided into 3 groups: 50 diagnosed were of chronic renal failure without dialysis in group I, 50 diagnosed case of chronic renal failure on dialysis from 3 month or more in group II and 50 healthy individuals as control in group III.
Results: It was observed that serum homocysteine level were significantly increased on both the chronic renal failure patient either in dialysis or without dialysis condition but it was noted that serum homocysteine level were more elevated in patients of renal failure on dialysis compared to without dialysis renal patients.

Key words:Homocysteine, GFR, Chronic renal failure, Dialysis, Glomerulonephritis.

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