Original Research Article
Year: 2017 | Month: Aug | Volume: 7 | Issue: 8 | Pages: 78-81
Thrombocytopenia in Intensive Care Unit: About 50 Cases
Jawad Rochdi, Souhil Mouline, Moulay IdrissMajouti, Abdelkader Belmekki
Laboratory of Hematology, Military Teaching Hospital, Mohamed Rabat Morocco
Corresponding Author: Jawad Rochdi
Introduction: The occurrence of thrombocytopenia is a common complication, which can be found in many pathological situations, in critically ill patients. The objective of this study is to determine the incidence of thrombocytopenia in intensive care unit (ICU) and its effect on patient outcome.
Methods: Data including patients hospitalized in intensive care unit during period from March 2011 to July2011 and having presented, at least one time, a platelet count <150 × 109/l. Included patients were prospectively followed until their discharge from ICU or their death.
Results and discussion: During our study, 130 patients were admitted to the intensive care unit and 50 cases of thrombocytopenia were recorded (38%). Thrombocytopenia in admission was noted in 25% of patients. The main risk factors associated with the occurrence of thrombocytopenia were sepsis, bleeding, acute respiratory distress syndrome, multiple trauma, and the presence of invasive intravascular catheters. The decision to transfuse platelets is dependent on the severity of the thrombocytopenia, its etiology and clinical impact. Mortality rate was 56%.
Conclusion: Thrombocytopenia is common in ICUs. Bleeding and sepsis are the major risk factors. Thrombocytopenia was a predictive factor of ICU mortality. Any therapies should be discussed case by case, but should never be generalized to all patients.
Key words: ICU, thrombocytopenia, risk factors, mortality.