International Journal of Health Sciences and Research

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Original Research Article

Year: 2017 | Month: July | Volume: 7 | Issue: 7 | Pages: 164-170

Contributing Factors Associated with Multi-Drugs Resistance Tuberculosis among MDR-TB Clients of Kathmandu, Nepal

Sanju Bhattarai1, Shanti Awale2

1Lecturer, Lalitpur Nursing Campus, Sanepa, Lalitpur, Nepal.
2Associate Professor, Lalitpur Nursing Campus, Sanepa, Lalitpur, Nepal.

Corresponding Author: Sanju Bhattarai


Introduction: The emergence of Multi-Drug Resistant Tuberculosis (MDR-TB) has become a significant public health problem and an obstacle to effective TB control measure.
Objective: The objective of this study was to assess the contributing factors of MDR-TB.
Materials and Methods: This study entitled “Contributing Factors Associated with Multi-Drugs Resistance Tuberculosis among MDR-TB Clients of Kathmandu, Nepal” was a descriptive cross sectional study. The study population consisted of 103 MDR-TB clients of National Tuberculosis Center, Bhaktapur, and German Nepal Tuberculosis Project (GENETUP) Kathmandu. Non probability purposive sampling method was used and data was collected using semi-structured questionnaire through face to face interview. Descriptive statistics was used for data analysis with the help of SPSS version 20.
Results: Of the total 103 respondents, 79.6% of the respondents were literate, 97.1% were employed at the time of diagnosis, 69.9% lived in rural areas, and 65.05% lived in crowded room at the time of MDR-TB diagnosis. Likewise 89.3% had past TB history, among them 75% had unfavorable treatment outcome of past TB and 35.9% respondents had interrupted TB treatment in past. Nearly seventy percent respondents had close contact with TB patients in past. Regarding personal habits 35.9% had ever smoked, 62.1% are passive smoker and 46.6% ever drank alcohol. Regarding co-morbidity 10.7% had suffered from COPD and 1.9% had HIV and diabetics each.
Conclusion: Overcrowding, close contact with TB patient, passive smoking, past TB treatment, self administered modality in past TB treatment and unfavorable outcome of past TB treatment have been observed as the contributing factors for MDR-TB.

Key words: MDR-TB, Contributing factors, Nepal

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