Original Research Article
Year: 2017 | Month: April | Volume: 7 | Issue: 4 | Pages: 29-33
Efficacy of Adding Buprenorphine to the Local Anaesthetics in Patients Undergoing Lower Segment Caesarean Section (LSCS)
Haribabu R1, Revathi P2
1Department of Anesthesiology, Ponniah Ramajayam Institute of Medical Sciences, [Affiliated to The Tamilnadu Dr. M.G.R. Medical University, Chennai], Kancheepuram, India.
2Department of Pharmacology, Chennai Medical College Hospital and Research Centre (SRM Group), [Affiliated to the Tamilnadu Dr. M.G.R. Medical University, Chennai], Tiruchirapalli, India
Corresponding Author: Haribabu R
ABSTRACT
Buprenorphine is a mixed agonist-antagonist narcotic with high affinity at both µ and k opiate receptors. The aim of the study was to compare intrathecal bupivacaine (0.5%) and buprenorphine (3mcg/kg) with bupivacaine (0.5%) an hour prior to surgery. One Hundred cases of LSCS of ASA-I, between age group 25-30 patients were taken for the study. First Fifty patients were given, 2ml of plain bupivacaine-Heavy 0.5%. Another fifty patients were given 2ml of Bupivacaine-heavy along with 0.5ml (3mcg/kg) of Buprenorphine pre-operatively, for all patients, BP, Pulse, SPO2 monitored. In this study, there is an action of increasing the sensory block without affecting motorblock and haemodynamic alterations where the onset of analgesia was significantly ear¬lier due to addition of buprenorphine mainly due to high lipid solubility and highest affinity for opiate receptors of buprenorphine By observing the results, It was concluded that buprenorphine is a suitable drug for postoperative analgesia after caesarean section with minimal side effects.
Key words: Bupivacaine, buprenorphine, caesarean section, analgesia.