Original Research Article
Year: 2017 | Month: April | Volume: 7 | Issue: 4 | Pages: 171-175
Comparative Evaluation of Pre-Induction Use of Misoprostol in Post-Term Pregnancies for Cervical Ripening on Outpatient Basis
Reena Pal1, Sandhya Deora2
1Assistant Professor, 2Senior Resident,
Department of Obstetrics & Gynaecology, Government Doon Medical College, Dehradun, Uttarakhand
Corresponding Author: Reena Pal
Objective: To compare the efficacy of sweeping and stretching of membranes versus sweeping and stretching combined with single dose 50 mcg misoprostol sublingually on ripening of cervix in singleton uncomplicated post term pregnancies on an outpatient basis.
Design: Randomized prospective comparative study.
Setting: Tertiary care teaching hospital, Government Doon Medical College, Dehradun.
Method: A total of 100 women with uncomplicated post term pregnancy, single live cephalic presentation with bishop score less than 5 were included in this study and were equally randomized to the two groups. Membrane sweeping and stretching was done in group A while women in group B received tab misoprostol 50mcg sublingually along with membrane sweeping.
Results: Pre-induction cervical ripening with sublingual misoprostol along with membrane sweeping stretching in post-term pregnancy showed significant shorter latency period as compared to group A (pre-induction cervical ripening with only membrane sweeping) with p value <0.05. Duration of labor was also lesser in group B as compared to group A(p value=<0.05). The need for further augmentation was also very significantly reduced in group B as compared to group A (p value=0.001).There were no significant difference in mode of delivery in both groups. Neonatal outcomes were comparable in both the groups.
Conclusion: Single dose sublingual tab misoprostol along with membrane sweeping stretching is safe and effective measure for pre-induction cervical ripening in post-term pregnancy on outpatient basis.
Key words: Pre-induction cervical ripening, Misoprostol, Membrane sweeping and stretching, Outpatient basis, Post-term pregnancy.