Original Research Article
Year: 2017 | Month: March | Volume: 7 | Issue: 3 | Pages: 32-35
Pregnancy Outcome in Women with Hypothyroidism
Dr. Manisha Jain1, Dr. Kushla Pathania2, Dr. Uday Bhanu Rana3, Dr. Kumud Bala Gupta4
1Fellowship Candidate at Jindal IVF and Sant Memorial Hospital, Chandigarh.
2Professor, Department Of OBG, Kamla Nehru Hospital, IGMC, Shimla, Himachal Pradesh.
3Senior Resident, Department Of OBG, Kamla Nehru Hospital, IGMC, Shimla, Himachal Pradesh.
4Senior Consultant, Tenzin Hospital, Shimla, Himachal Pradesh.
Corresponding Author: Dr. Uday Bhanu Rana
Objective: The present study was to know the pregnancy outcome in women with hypothyroidism.
Methods: This randomized prospective study was carried out in the department of Obstetrics and Gynecology, Kamla Nehru State Hospital for Mother and Child, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India. A total of 2000 pregnant women underwent thyroid function tests (free T3, free T4, and TSH) at their first antenatal visit. Quantitative thyroid hormones were measured by ELISA in serum.
Results: The data was tabulated and statistically analyzed by applying Student t-test and chi-square test to know the incidence of hypothyroidism in pregnant women and correlate the associations between thyroid disorders and various maternal and perinatal outcomes. A total of 2000 consecutive pregnant women attending the antenatal OPD were included in the study. Out of these 254 women were diagnosed to have hypothyroidism (12.7%). Incidence of preterm labor, placental abruption, IUGR was significantly increased in study group.
Conclusion: Systematic screening for hypothyroidism early in pregnancy may be worthwhile and should be commenced at first antenatal visit, preferably in the first trimester. Optimum thyroxine supplementation will obviate many of the maternal and fetal morbidities.
Key words: Hypothyroidism, free T3, free T4, TSH, Preterm labor