International Journal of Health Sciences and Research

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Original Research Article

Year: 2017 | Month: March | Volume: 7 | Issue: 3 | Pages: 56-64

Study of Adverse Donor Reactions in Whole Blood Donors in a Tertiary Care Hospital

Rubiya Ryhan1, Vijay Sawhney1, Meena Sidhu1, Shazia Handoo2

1Post Graduate Department of Immunohematology and Transfusion Medicine GMC, Jammu
2Department of Hematology and Transfusion Medicine GMC, Srinagar

Corresponding Author: Rubiya Ryhan


Aim: To estimate the frequency, severity & association of adverse events occurring in whole blood donors. And to assess the predisposing risk factors of these adverse events
Materials & Methods: The present study is a one year hospital based cross-sectional study & the donors who developed adverse reactions were categorized with respect to: age, sex, hemoglobin, type of donor, & place of donation.
Results: During this one year study period, a total of 35256 donors donated blood, out of which 1928 (5.5 %) donors experienced donation related adverse effects. Reaction rate among male & female donors were 5.3% (1730/23928) & 8.5 % (198/2328) respectively. Most of the donors 90.6 % (1746/ 1828) who experienced adverse donor reactions belong to the younger age groups. Age & gender had a significant effect on rate of reaction (p <0.0001). Higher rate of adverse reactions 7.9 % (562/7050) was observed in donors with hemoglobin in the range of 12.5 – 13.4 g/dl. Also Significantly higher (p <0.01) rate of adverse reactions was observed among 1st time donors 8.7% (1376/15866), replacement donors 6.6% (1048/15864) & donors who donated blood in outside donation camps 6.1% (426/7052).
Summary & Conclusion: Donation related adverse reactions are multifactorial determined by age, sex, hemoglobin, type & status of donor & place of donation. Our study reinforces that blood donation is a safe procedure which could be made even more event free by analyzing adverse events, identifying the donors at risk of donor reactions and adopting appropriate donor motivational strategies, pre-donation counseling, and care during and after donation, strict adherence to guidelines in donor examination & selection.

Key words: Blood Donor, Adverse Donor Reactions, Donor Safety.

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