Review Article
Year: 2017 | Month: February | Volume: 7 | Issue: 2 | Pages: 294-303
Pulmonary Renal Syndrome: Update Article
N.S.Neki1, Satpal Aloona2
1Professor, 2Assistant Professor,
Department of Medicine, Govt. Medical College/ Guru Nanak Dev Hospital, Amritsar, India- 143001
Corresponding Author: N.S. Neki
ABSTRACT
The pulmonary–renal syndrome (PRS) refers to the combination of diffuse alveolar haemorrhage and rapidly progressive glomerulonephritis (RPGN). Pulmonary-renal syndrome can originate from various systemic autoimmune diseases. ANCA-associated vasculitides account for approximately 60%, Goodpasture's Syndrome for approximately 20% of the cases. It is almost always autoimmune in nature, therefore steroids and other immunosupressants have role in its treatment. The underlying renal pathology is a form of focal proliferative glomerulonephritis. The lung pathology is in form of diffuse alveolar hemorrhages.
Key words: Pulmonary renal syndrome; Wegener's granulomatosis; microscopic polyangiitis; systemic lupus erythematosus.