Original Research Article
Year: 2017 | Month: January | Volume: 7 | Issue: 1 | Pages: 58-62
A Clinicopathological Study of Urinary Bladder Neoplasms on Trans Urethral Resected Bladder Tumours (Turbtchips) - At a Tertiary Care Centre
Zaheda Kausar1, Kotta Devender reddy2, Ezhil Arasi3, Anunayi J2, Shakera Anjum1
1Assistant Professor, 2Associate professor, 3Professor and HOD,
Upgraded Department of Pathology, Osmania General Hospital, Hyderabad
Corresponding Author: Zaheda Kausar
ABSTRACT
Background: Bladder cancer is the 7th most common cancer worldwide, with an estimate of 260,000 new cases occurring each year in men and 76,000 in women. The origin of Bladder tumour is multifactorial, with tobacco smoke as principal cause in most countries. Other etiologic factors include analgesic abuse, occupational exposure and chronic Schistosoma cystitis. Aim and objectives: The aim of the present study is to analyse the spectrum of lesions in Urinary bladder by histopathological examination of TURBT specimens.
Material and methods: The study was carried out in the Upgraded department of Pathology, Osmania General Hospital, and Hyderabad for a period of 18 months. Clinicopathological data of all the TURBT biopsies were collected and analysed. Results: A total of 64 TURBT biopsies were received in the study period and included both benign and malignant neoplasms. Urothelial carcinomas were classified according to WHO/ISUP (2004) classification. The most common age group was 61-70 years (34%) with male to female ratio of 3.26:1. Among the urinary bladder neoplasms most of them were malignant lesions and the most common type of malignancy was Papillary urothelial carcinoma-high grade (65.6%) followed by low grade papillary urothelial carcinoma (10%), well differentiated squamous cell carcinoma (9%), transitional cell papilloma (4%), papillary urothelial neoplasm of low malignant potential (3%), moderately differentiated adenocarcinoma (3%).
Conclusion: Among urinary bladder neoplasms high grade papillary urothelial carcinoma is the most common type. Improvements in early detection have made reproducible grading and staging important criteria for clinical management and prognosis.
Key words: Urothelial carcinoma, Squamous cell carcinoma, Adenocarcinoma, Urinary bladder, TURBT.