Case Report
Year: 2017 | Month: January | Volume: 7 | Issue: 1 | Pages: 307-309
Cholestatic Jaundice Induced by Sequential Carbimazole and Propylthiouracil Treatment for Thyrotoxicosis-A Case Report
N.S.NEKI1, Satpal Aloona2
1Prof Medicine 2Assistant Prof Medicine,
Govt. Medical College/Guru Nanak Dev Hospital, Amritsar, 143001, Punjab, India.
Corresponding Author: N.S.NEKI
ABSTRACT
Grave’s disease is the most common cause of hyperthyroidism. Antithyroid drugs are usually well tolerated in majority of patients but dangerous adverse effects can occur in 3-12% of treated patients. Cholestatic jaundice is a rare but potentially fatal complication secondary to the use of antithyroid drugs like carbimazole and propylthiouracil. We report a case of 46 year old male patient who developed cholestatic jaundice following sequential administration of carbimazole and propylthiouracil treatment for thyrotoxicosis.
Key words:Thyrotoxicosis; Cholestatic jaundice; Carbimazole; Propylthiouracil.