Original Research Article
Year: 2017 | Month: January | Volume: 7 | Issue: 1 | Pages: 15-19
A Study of Lipid Profile with Reference to Cardiovascular and Cerebrovascular Events among Hypertension Patients at a Tertiary Care Centre, Tamil Nadu, India
Vijaya Kumar Gladstone1, Senthil Kumar2, Jercy Grace3
1Professor, 2Asst Professor, 3Post Graduate,
Department of Internal Medicine, Meenakshi Medical College Hospital and Research Institute, Kanchipuram - 631552 (Tamil Nadu)
Corresponding Author: Jercy Grace
ABSTRACT
This study ,conducted in the locality of Kanchipuram over a period of 1 1/2 years , was meant to analyze the Serum lipid profiles of Hypertensive Patients with respect to various clinical profiles and its incidence. As to gain a better understanding of the relation between blood pressure and blood lipids which may provide insight into the mechanisms where by hypertension is associated with increased risk of Coronary Artery Disease and Cerebrovascular disease. The serum lipid profiles (TC,TGL.HDL, VLDL, LDL, TC/ HDL, LDL/ HDL ratios) of 100 hypertensive patients was studied and compared with CVA group with Non-CVA group and IHD group with Non - IHD group .Study group consisted of patients with hypertension as identified by history, clinical examination, and other relevant examinations. TC and LDL were raised in CVA group, which was statistically very significant. TC/ HDL and LDL/HDL were also raised in CVA group as compared to non-CVA group, which was statistically very significant. TC and LDL is raised in IHD group with Hypertension, which was statistically very significant. There was significant alteration of lipid profile in hypertensive patients among who have developed CVA and IHD and those who have not yet.
Key words: Hypertension; TC; LDL; HDL; VLDL; TGL; Cerebrovascular accident; Ischemic heart disease.