Original Research Article
Year: 2017 | Month: January | Volume: 7 | Issue: 1 | Pages: 1-9
Nutritional, Epidemiological and Pathological Profiles of Colorectal Cancer in Jijel Province: A Case Control Study
Abbes Arbia1,2, Rechreche H1, MeniaMohamed1, Boumala Ilham1, Benalia Selma1, Benali Mohamed2
1Molecular and Cellular Biology Laboratory (MCBL), MSB University, Jijel, Algeria.
2Biotoxicology Laboratory, DjillaliLiabes University, SidiBelAbbes, Algeria.
Corresponding Author: Rechreche H
ABSTRACT
Colorectal cancer or CRC is one of the most prevalent cancers worldwide; its incidence rate in Algeria has been incrementally and steadily increased because of socio-economic transition during the last decades. Diet has been reported to play a major role in the CRC etiology. The present study aimed to gain a better understanding of the relationship between some lifestyle factors such as the food groups’ frequency consumption and CRC in Jijel Wilaya (Algeria). We conducted a case control study among the CRC patientssupported by the Jijel Hospital. The comparison of 34 cases with their controls revealed that the high educational level (OR= 0.0578, p-value= 0.0075), the low household income (OR=7.8386, p value=0.0374), the smoking (OR=0.0751, p-value=0.0174) and the familial history of CRC (OR=5.2500, p-value=0.0034) may be associated with the CRC occurrence in this population. A protective effect of consumption of dairy products (OR=0.9808, p-value=0.0437) and cereals (OR=0.9865, p-value= 0.0100) was observed, while the fish consumption appearedto be positively associated with CRC (OR=1.0665, p-value=0.0392). We showed that of the proximal colon tumors were associated with a low consumption of fruits, vegetables and cereals and a consumption of dairy products. By contrast, the distal and rectal colon tumors seemed to be dependent to the excessive consumption of fruits, vegetables and cereals. Unexpectedly, the red meat consumption did not exerciseany effect on the sub-sites of the tumors occurrence.
Key words: colorectal cancer, Diet, cancer incidence, protective effect.