Year: 2017 | Month: November | Volume: 7 | Issue: 11 | Pages: 317-320
Primary Sjogren’s Syndrome with Involvement of Both Tubulointerstitial and Glomerulo-Nephritis- a Rare Case Report
Dr. Saranya C1, Dr. Balameena Selvakumar2, Dr. Bhuvanesh Mahendran1, Dr. Madeshwaran Mani1, Dr. Mythili Seetharaman1, Dr. Vignesh Mantharam1, Dr. Rajeswari Sankaralingam3
1D.M. Postgraduate, 2Assistant Professor, 3Director & Head,
Assistant Professor, Institute of Rheumatology, Madras Medical College & Rajiv Gandhi Government General Hospital, Chennai.
Corresponding Author: Dr. Saranya C
Sjogren’s syndrome is a rare autoimmune disease characterised by keratoconjuctivitis sicca due to autoimmune destruction of exocrine glands. Tubulointerstitial nephritis is the most common renal manifestation while glomerulonephritis is rare in Sjogren’s syndrome. Here we report a case of primary Sjogren’s (pSS) who presented as acute renal failure due to mesangial proliferative glomerulonephritis in addition to the coexistent tubulointerstitial nephritis.
Key words: Autoimmune disease, exocrine glands, Tubulointerstitial nephritis, glomerulonephritis.