Original Research Article
Year: 2016 | Month: November | Volume: 6 | Issue: 11 | Pages: 67-72
A Clinico-Morphological Spectrum of Nephrectomy Specimens - An Experience from a Tertiary Care Hospital
Kotta Devender Reddy1, Sri Lakshmi Gollapalli2, Chougani Sujitha3, Shivalalitha Sidagam3, Amanulla khan Mohmmed3, Archana Bommana4
1Associate Professor, 2Assistant Professor, 3Post Graduate, 4Senior Resident,
Department of Pathology, Osmania Medical College, Hyderabad, Telangana State, India.
Corresponding Author: Kotta Devender Reddy
ABSTRACT
Background: In recent years, there is an increase in the number of nephrectomies done as there is an extensive use of imaging techniques. Nephrectomy is a standard therapeutic urological procedure for irreversibly damaged non functioning kidneys involved by different benign pathological conditions and renal malignancies.
Aim: This study analyzed various kidney diseases histopathologically from nephrectomy specimens received in the department of pathology in our institute.
Methodology: This is a retrospective study conducted in Osmania General Hospital for duration of two years from August 2014 to July 2016.
Results: Seventy seven cases of nephrectomy specimens were received in the department of histopathology. Out of 77 patients, 33 were females and 44 were males. Most common age group was in 4th decade. The final diagnosis was arrived at after correlating the clinical features, gross, microscopic findings, immunohistochemistry wherever required. The spectrum of pathological lesions included both non-neoplastic and neoplastic lesions.
Conclusion: Chronic pyelonephritis was the most common lesion of all nephrectomies studied. Renal cell carcinoma was the most common malignant lesion encountered in our study. Other rare malignant lesions like sarcomatoid renal cell carcinoma, squamous cell carcinoma, PNET were studied. Angiomyolipoma and oncocytoma are the benign neoplastic lesions seen in our study.
Key words: Nephrectomy, Pyelonephritis, Renal cell carcinoma, Angiomyolipoma.