Case Report
Year: 2014 | Month: February | Volume: 4 | Issue: 2 | Pages: 213-216
Unusual Case of Bilateral Papillary Serous Cystadenocarcinoma of Ovary with Secondaries in Endomyometrium, Cervix and Appendix
Meera Mahajan1, Mukul Raj Jain2, Suparna Bindu3, Smita Mulay4
1Lecturer, 2Chief Resident, 3Asscociate Professor,4Professor & HOD,
Department of Pathology, MGM Medical College, Aurangabad, Maharashtra.
Corresponding Author: Meera Mahajan
ABSTRACT
52 years old female presented with pain in lower abdomen, white per vaginal discharge. Patient was known case of HIV with history of fibroadenoma in past. USG showed uterus with heterogeneous lesion with cystic spaces & enhancement in posterior myometrium. Ovaries showed well defined heterogeneous mass of size 72x84mm, not seen separate from right ovary with cystic spaces & irregular mural nodule. CA 125 level was 1242. Pap smear was done. Hysterectomy with bilateral salpingoophorectomy with appendectomy done. Uterus size 9*5*5 cm. Uterus was bulgy. Cut section showed well circumscribed capsulated tumor mass which showed cabbage like appearance and whorled pattern. Length of cervix 2.5 cm. Cervical canal was totally obliterated. Right ovary showed partly cystic and partly solid areas. Cystic part showed serous fluid and solid areas showed variegated appearance. Left ovary received in three pieces. Appendix externally congested, swollen, tip intact and lumen obliterated. Microscopically endomyometrium showed infiltration by tumor tissue. Myometrium showed well circumscribed tumor tissue with spindle cells having whorled pattern. Bilateral ovaries showed tumor tissue in which cells arranged in groups, papillary and glandular pattern and infiltrating into ovarian stroma. Appendix showed ulcerated lining mucosa and mucosal glands. Underneath submucosa and muscularis were infiltrated by tumor tissue. Pap smear showed few round to oval large cells with hyperchromatic eccentrically placed nuclei arranged in glandular pattern. Diagnosis given as Papillary serous cystadenocarcinoma of right and left ovaries with secondaries in endomyometrium, cervix and appendix.
Key words: Serous cystadenocarcinoma, metastasis.